Pig kidney keeps US patient off dialysis for 9 months
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Pig kidney keeps US patient off dialysis for 9 months

Livemint··5 Sept

A genetically modified pig kidney kept 66-year-old Tim Andrews of New Hampshire off dialysis for nine months before a human transplant. Surgeons implanted the organ from Yucatan miniature pig Wilma in January 2025. It worked for 271 days, the longest such period reported in a living patient. The Lancet calls it the first pig-kidney bridge to a human donor kidney.

Prism

What It Means For You

  • Researchers present the pig kidney as a temporary bridge off dialysis while waiting for a human organ.
  • Andrews's chance of a human kidney within five years had been put at 9 percent.
  • No pig viruses were detected, and no new antibodies against human tissue were found.

What's Happening

  • Scientists made 69 genetic edits to Wilma's genome before the transplant.
  • The pig kidney began failing after about six months and was removed at nine months.
  • Andrews later received a deceased human donor kidney after a further spell on dialysis.

Why the Case Matters

  • Andrews had end-stage kidney disease from type 2 diabetes.
  • His risk of dying or leaving the waiting list within five years was put above 40 percent.
  • Dr Leonardo Riella said further trials are still needed after this single-patient report.
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